Temporin-SHa, Antimicrobial Peptide (AMP) (CAT#: BMWJ-0826-WJ110)

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Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC50 = 5-20 μM), and Trypanosoma cruzi (IC50 = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.).

Overview
SynonymsTemporin-SHa; Temporin SHa
SourceAmphibian
SequencePhe-Leu-Ser-Gly-Ile-Val-Gly-Met-Leu-Gly-Lys-Leu-Phe-NH2
Sequence ShorteningFLSGIVGMLGKLF-NH2
ActivityGram-positive bacteria; Gram-negative bacteria; Fungi; Virus; Protozoa; Cancer; Amphibian
Physical StatePowder
Purity>98%
StorageThe power can be stored at 4°C for 2 years or at -20°C for 3 years.

For Research Use Only.

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