As a leading company in the field of drug industry, Creative Biolabs has gained a wealth of good reputation for successfully completed numerous challenges in antifungal drug discovery. Based on our advanced technology platform and experienced scientists, we are able to offer a series of antifungal drug discovery services against tinea cruris.

What is Tinea Cruris?

Tinea Cruris, also known as jock itch, is an acute or subacute superficial fungal infection of the groin region in either sex. Its infection areas include the genitalia, pubic area, perineal skin, and perianal skin. Common pathogenic fungus contributing to otinea cruris infections are as following:

Among these species, T. rubrum tends to trigger the chronic infections, while the zoophilic species T. mentagrophytes usually causes acute dermatophytosis.

Risks of Tinea Cruris Infection

Tinea cruris can be spread by direct contact or by autoinfection of other dermatophytes elsewhere in the body. Like most other dermatophyte infections, several factors may increase the risk of tinea cruris infections:

  • Age and sex: young adults and males;
  • Environment: high temperature and humidity environment in tropical areas;
  • Physical factors: diabetes mellitus, obesity, immunocompromised state.

Tinea Cruris infection.Fig.1 Tinea Cruris infection.

Symptoms and Signs

Characteristic symptoms of tinea cruris include a red or brown irritated patch of skin with clear rings, burning sensation and pruritus that commonly begin unilaterally in the crural fold. Usually, it begins unilaterally in the crural fold, groin or anus, involves the inner thighs, genital areas, as well as the perineum and perianal areas.

Tinea cruris is highly contagious, which can easily spread to any parts of the body. Macerated, moist exudative forms or lesions with an eczematous appearance can be present in acute cases, while dry lesions with little scaling and an annular form are more common in chronic cases.

Diagnosis and Prevention

  • Tinea cruris is closely similar to candidal intertrigo, which is an infection of the skin by Candida albicans. The coral red fluorescence seen on Wood lamp examination and fungal culture can be used for the differentiation of tinea cruris.
  • Keeping groin dry, controlling other forms of dermatophytosis infection and good hygiene can help to reduce the risk of tinea cruris.

Treatment

Like other cutaneous fungus infections, topical therapy is priority selection, with topical antifungal medications of the allylamine or azole types. It is better to choose oral treatments when the infection is in immunocompromised patients. Fluconazole, itraconazole, and terbinafine has high clinical and mycologic cure rates for antifungal medications oral treatments.

Types of Dermatophytosis Studied by Creative Biolabs

As a part of our antifungal drug research, Creative Biolabs has abundant and professional experience in dermatophytosis research. Our professional scientists will work closely with our customer and provide you with high-quality, flexible, and cost-effective services. Besides tinea cruris, other types of dermatophytosis are also within our scope of service.

If you are interested in the fungal diseases we investigate, please click the links above. For more detailed information, just feel free to contact us.

For lab research use only.



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