As a leading company in the field of the drug industry, Creative Biolabs has gained a wealth of good reputation for successfully completed numerous challenges in antifungal drug discovery. Based on our advanced technology platform and experienced scientists, we are able to offer a series of antifungal drug discovery services against tinea manuum.

What is Tinea Manuum?

Tinea Manuum, also known as tinea manus, is a dermatophyte infection of hands and interdigital spaces. It is frequently associated with tinea pedis but more aggressive than it. Tinea manuum is commonly caused by anthropophilic dermatophytes and several zoophilic causative organisms, successively as follows:

Risks of Tinea Manuum Infection

Tinea manuum virtually tends to occur in a patient who has coexisting tinea pedis. Contacting with another site of infection, particularly the tinea pedis or tinea cruris, or directly contacting with an infected animal or soil are main predisposing factors for tinea manuum.

Presentations of Tinea Manuum. Fig.1 Presentations of Tinea Manuum.

Symptoms and Signs

Typical presentations of tinea manuum are a diffuse white scaling/hyperkeratosis with or without mild itching, unilateral diffuse hyperkeratosis with accentuation of the flexural creases. Generally, tinea manuum involves only one hand, resulting in the “one hand, two feet” syndrome.

Diagnosis and Prevention

  • As similar to hand dermatitis, tinea manuum is frequently misdiagnosed. Therefore, confirmation by both microscopy and culture of skin scrapings, or KOH preparation are necessary for the diagnosis of tinea manuum.
  • The overall prevalence of tinea manuum can be decreased by avoiding direct contact with infection and good hygiene.

Treatment

Treatment with topical antifungal agents would be better when infection is mild, and the available antifungal medications include:

  • Imidazole creams (clotrimazole, miconazole, econazole, ketoconazole, luliconazole, sertaconazole, sulconazole);
  • Allylamines (butenafine, naftifine, terbinafine);
  • Ciclopirox olamine.

But if the treatment is unsuccessful or infection is serious, oral antifungal medicines should be applied, including terbinafine and itraconazole.

Types of Dermatophytosis Studied by Creative Biolabs

Aided by top technology and professional scientists, Creative Biolabs is committed to promoting the development of global customers’ programs. In addition to tinea manuum, we also provide potential antifungal drug discovery services against other fungal diseases, which including but not limited to:

If you are interested in the fungal diseases we investigate, please click the links above. For more detailed information, just feel free to contact us.

For lab research use only.



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