Exosome Manufacturing Services
Exosome manufacturing is aimed at scaling up manufacturing yields and controlling purity, increasing manufacturing efficiency and output to meet high-volume exosome needs. Creative Biolabs offers solutions for large-scale extraction and purification of exosomes, suitable for the requirements of industrial exosome manufacturing. Our services not only support scalable upstream manufacturing of exosomes, but also take into account the characterization, profiling and downstream potential exploration of exosome products to provide customized functional exosomes.
Types of Manufactured Exosomes
Exosome Manufacturing Process
Fig. 1 Tangential flow filtration principle and diagram. (Visan, 2022)
Evaluation Services for Manufactured Exosomes
Multiple exosome manufacturing process attributes including efficiency, flexibility, reliability, ease of use and automation are taken into account and collectively affect the yield, purity and physicochemical properties of the obtained exosomes. Therefore, Creative Biolabs is also equipped with a range of inspection services to confirm reliable exosome products that facilitate the subsequent application of exosomes.
Why Choose Us
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Mature and professional exosome manufacturing platform.
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Effectively increase exosome yield and purity.
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Circumvent size overlap between exosomes and other extracellular vesicles (e.g., microvesicles) or potential contamination (e.g., lipoprotein aggregates).
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Retention of exosomal potency inherited from the donor.
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One-stop service for upstream manufacturing and downstream exploration.
Fig. 2 Challenges in exosome applications. (Dai, 2022)
Advancing the research and application expansion of exosomes requires overcoming the problem of balancing yield and purity in large-scale exosome manufacturing. Creative Biolabs has built a complete exosome manufacturing platform to provide comprehensive services for exosome manufacturing, profiling and quality validation. Please contact us to discuss your needs.
References
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Visan, K.S.; et al. Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small extracellular vesicles. J Extracell Vesicles. 2022, 11(9): e12266.
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Dai, X.; et al. Emerging innovations on exosome-based onco-therapeutics. Front Immunol. 2022, 13: 865245.
For Research Use Only. Cannot be used by patients.
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