Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsFXYD domain-containing ion transport regulator is a family of small transmembrane proteins which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD family performs fine tuning of ion transport through associating with and modulating the pump activity of Na+, K+-ATPase molecules and modifying the activity of ion channels. In mammals, the FXYD family contains seven members including FXYD1 (phospholemman), FXYD2 (the gamma-subunit of Na+, K+-ATPase), FXYD3 (Mat-8), FXYD4 (corticosteroid hormone-induced factor), FXYD5 (dysadherin), FXYD6 (phosphohippolin) and FXYD7. These proteins are predominantly expressed in specific tissues to modulate Na+, K+-ATPase activity, and precisely adjust the physiological ion balance of the tissues.
Below are some of FXYD domain-containing ion transport regulator proteins in humans. The FXYD family members have been shown to be implicated in various physiological mechanisms and related diseases, such as maintaining the excitability of neurons, metastasis. And thus, these proteins have been linked to a variety of cancers, including breast cancer, lung cancer, prostate cancer, urothelial cancer, colon cancer.
| Human FXYD Domain-containing Ion Transport Regulator Members | |||
| FXYD1 | FXYD2 | FXYD3 | FXYD4 |
| FXYD5 | FXYD6 | FXYD7 | |
By using our state-of-the-art MemDX™ membrane protein production platform, scientists in Creative Biolabs are proud to offer the high quality, reliable solutions to support our clients, using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Furthermore, our MemDX™ membrane protein antibody discovery platform also can assist you in discover antibodies against these targets, even fully humanized antibodies, by various approaches including hybridoma technology, phage display technology, etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
