shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(C20orf43-shRNA-Seq1B)(CAT#: AdV-SI3701WQ)

This product is a C20orf43-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The C20orf43 gene may be required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication and function to facilitate fork pausing at replication fork barriers like the rDNA. The expression of C20orf43-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.