shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Med18-shRNA-Seq5)(CAT#: AdV-SI3582WQ)

This product is a Med18-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Med18 gene is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II. The expression of Med18-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Med18-shRNA-Seq5
Related Target/Protein Med18
Region 3UTR
TargetSeq GAATTAAAGGCGTGCGATAAC
NCBI RefSeq NM_026039
Alternative Names SRB5; p28b
Titer >1*10^10 GC/mL
Target Gene
Gene ID 54797
Uniprot ID Q9BUE0

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