shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(SH3D19-shRNA-Seq1)(CAT#: AdV-SI0777WQ)

This product is a SH3D19-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The SH3D19 gene encoded protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. The expression of SH3D19-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.