shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(Zcchc5-shRNA-Seq1)(CAT#: AdV-SI3068WQ)
This product is a Zcchc5-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Zcchc5 gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose. The expression of Zcchc5-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Zcchc5-shRNA-Seq1 |
| Related Target/Protein | Zcchc5 |
| Region | CDS |
| TargetSeq | CCACCAACCTATCTGATGTGA |
| NCBI RefSeq | NM_199468 |
| Alternative Names | Mar3; ZHC5; Mart3; SIRH9; ZCCHC5; RTL3 |
| Titer | >1*10^10 GC/mL |