shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Adipor1-shRNA-Seq1)(CAT#: AdV-SI1833WQ)
This product is a Adipor1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Adipor1 gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. The expression of Adipor1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | Adipor1-shRNA-Seq1 |
| Related Target/Protein | Adipor1 |
| Region | CDS |
| TargetSeq | GACAACGACTACCTGCTACAT |
| NCBI RefSeq | NM_028320 |
| Alternative Names | CGI45; PAQR1; ACDCR1; CGI-45; TESBP1A |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Obesity; Diabetes |
