shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(C20orf43-shRNA-Seq2)(CAT#: AdV-SI0360WQ)

This product is a C20orf43-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The C20orf43 gene is required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. The expression of C20orf43-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert C20orf43-shRNA-Seq2
Related Target/Protein C20orf43
Region CDS
TargetSeq CCTGTGAACTTGGCAGACTTT
NCBI RefSeq NM_016407
Alternative Names CDAO5; RTFDC1; HSPC164; RTF2; SHUJUN-3
Titer >1*10^10 GC/mL
Target Gene
Gene ID 51507
Uniprot ID Q9BY42

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