shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(DZIP1L-shRNA-Seq2)(CAT#: AdV-SI0136WQ)

This product is a DZIP1L-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The DZIP1L gene encoded proterin is involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane. The expression of DZIP1L-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.