shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(FANCI-shRNA-Seq2)(CAT#: AdV-SI0339WQ)
This product is a FANCI-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The FANCI gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. The expression of FANCI-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | HAdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Insert | FANCI-shRNA-Seq2 |
| Related Target/Protein | FANCI |
| Region | CDS |
| TargetSeq | CCATTACAATTCTGTCGCCAA |
| NCBI RefSeq | NM_018193 |
| Alternative Names | KIAA1794 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | DNA Damage |
