shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Gramd1a-shRNA-Seq1)(CAT#: AdV-SI2214WQ)

This product is a Gramd1a-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Gramd1a gene is cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). The expression of Gramd1a-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.