shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(HOOK2-shRNA-Seq2)(CAT#: AdV-SI1618WQ)

This product is a HOOK2-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The HOOK2 gene encodes a member of Hook proteins that are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The expression of HOOK2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.