shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(MAGEB2-shRNA-Seq2)(CAT#: AdV-SI0129WQ)

This product is a MAGEB2-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. MAGEB2 gene is a member of the MAGEB gene family. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The expression of MAGEB2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert MAGEB2-shRNA-Seq2
Related Target/Protein MAGEB2
Region 3UTR
TargetSeq CAATCTCCCAAAGCCAAGTTT
NCBI RefSeq NM_002364
Alternative Names DAM6; CT3.2; MAGE-XP-2
Titer >1*10^10 GC/mL
Related Diseases Testis cancer
Target Gene
Gene ID 4113
Uniprot ID O15479

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