shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Mepe-shRNA-Seq1)(CAT#: AdV-SI2304WQ)

This product is a Mepe-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Mepe gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. The expression of Mepe-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Mepe-shRNA-Seq1
Related Target/Protein Mepe
Region CDS
TargetSeq GCTCCAGCAAAGCTGAAGTTA
NCBI RefSeq NM_053172
Alternative Names OF45
Titer >1*10^10 GC/mL
Related Diseases Aging-related trabecular bone loss
Target Gene
Gene ID 56955
Uniprot ID Q9NQ76

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