shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Olfr376-shRNA-Seq5)(CAT#: AdV-SI2029WQ)

This product is a Olfr376-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Olfr376 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of Olfr376-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Olfr376-shRNA-Seq5
Related Target/Protein Olfr376
Region CDS
TargetSeq CTGATCCTTGTCATTCCATTT
NCBI RefSeq NM_146922
Alternative Names MOR135-12
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 258924
Uniprot ID E9Q4M1

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