shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(OR10A3-shRNA-Seq1)(CAT#: AdV-SI1541WQ)
This product is a OR10A3-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR10A3 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR10A3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | OR10A3-shRNA-Seq1 |
Related Target/Protein | OR10A3 |
Region | CDS |
TargetSeq | CCTCTGAACTACCCAGTGATT |
NCBI RefSeq | XM_291986 |
Alternative Names | HTPCRX12; HSHTPCRX12 |
Titer | >1*10^10 GC/mL |
Related Diseases | Olfactory dysfunction |