shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(OR10C1-shRNA-Seq3)(CAT#: AdV-SI1586WQ)
This product is a OR10C1-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR10C1 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR10C1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | OR10C1-shRNA-Seq3 |
| Related Target/Protein | OR10C1 |
| Region | CDS |
| TargetSeq | CGCTTAATGAACTGCAGATTA |
| NCBI RefSeq | NM_013941 |
| Alternative Names | OR10C2; OR6-31; OR10C1P; hs6M1-17 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Olfactory dysfunction |
