shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(OR4S2-shRNA-Seq6)(CAT#: AdV-SI2133WQ)

This product is a OR4S2-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The OR4S2 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR4S2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert OR4S2-shRNA-Seq6
Related Target/Protein OR4S2
Region CDS
TargetSeq CCTGCATTGTTCATTTACATT
NCBI RefSeq XM_166871
Alternative Names OR4S2P; OST725; OR11-137
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 219431
Uniprot ID Q8NH73

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