shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(PATL1-shRNA-Seq1)(CAT#: AdV-SI0103WQ)

This product is a PATL1-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The PATL1 gene encodes a involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. The expression of PATL1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.