shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(PRDM15-shRNA-Seq3)(CAT#: AdV-SI0214WQ)
This product is a PRDM15-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The PRDM15 gene plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. The expression of PRDM15-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | HAdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Insert | PRDM15-shRNA-Seq3 |
| Related Target/Protein | PRDM15 |
| Region | CDS |
| TargetSeq | CCGACTGTTCTTTGTTACATT |
| NCBI RefSeq | NM_022115 |
| Alternative Names | PFM15; ZNF298; C21orf83 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Pancreatic cancer |
