shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(SF3A3-shRNA-Seq5)(CAT#: AdV-SI0058WQ)

This product is a SF3A3-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The SF3A3 gene encodes subunit 3 of the splicing factor 3a protein complex, which interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. The expression of SF3A3-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.