shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(TMEM177-shRNA-Seq4)(CAT#: AdV-SI1807WQ)
This product is a TMEM177-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The preotien encoded by TMEM177 gene plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation. The expression of TMEM177-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Adenoviridae |
| Species | Adenovirus |
| Serotype | AdV-5 |
| Backbone | AdV-5 (ΔE1/E3) |
| Tropism | Both nondividing and dividing cells |
| Modification | ΔE1/E3 |
| Insert | TMEM177-shRNA-Seq4 |
| Related Target/Protein | TMEM177 |
| Region | 3UTR |
| TargetSeq | GTTGGAGCCTTTGGACCTATA |
| NCBI RefSeq | NM_030577 |
| Titer | >1*10^10 GC/mL |
