Antisense Oligonucleotides (ASOs) Products for HIV/AIDS
It is well known that HIV/AIDS is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Nowadays, antisense oligodeoxynucleotides (ASOs) are under investigation as new drugs used to stop HIV infection. During the cycle life of HIV, antisense drugs can be designed to block the reverse transcriptase and inhibit virus gene expression by antisense specific activity. Prior attempts to inhibit HIV by various antisense approaches have used oligonucleotides targeted to the initiation sites for translation, the cap site, the polyadenylation signal, the RT primer site, the splice donor/acceptor sites, and the site between the gag and pol genes, etc. In addition, it has found that antisense compounds that specifically bind the TAR (trans-acting responsive element) within RNA structure and interfere with tat trans-activation have activity as therapeutic agents for HIV infection.
Creative Biolabs is a world-renowned service provider for antisense oligonucleotides therapy development. We provide a variety of top-quality ASO products for HIV/AIDS therapy. In addition, a series of stringent criteria are applied to implement quality control of antisense products in order to guarantee reliability. We are dedicated to providing the best-characterized antisense therapy service to promote customers' project applications. Please feel free to contact us by e-mail for a quote and further technical support.
Reference
- Galderisi, U.; et al. (2001). Antisense oligonucleotides as drugs for HIV treatment. Expert Opinion on Therapeutic Patents. 11(10), pp.1605-1611.
