Recombinant Lentivirus
As a frontier biotech service provider, Creative Biolabs provides superior recombinant lentivirus products for our clients all over the world. With high standards of quality control, the recombinant lentivirus vectors are able to be used safely in preclinical gene therapy development, including vascular diseases, diabetes mellitus, rheumatoid arthritis and different cancers, etc. We are dedicated to developing first-in-class recombinant lentivirus that best fits your requirements and expedites your development programs.
The best characterized lentiviral vectors are derived from the human immunodeficiency virus type 1 (HIV-1) which belongs to the lentivirus genus of Retroviridae and has evolved a nuclear-import machinery that allows them to infect both dividing and nondividing cells. The lentiviral vectors are successful and efficient gene delivery vehicles that are able to provide long-term gene expression and highly effective gene therapy. Currently, the lentiviral vectors, especially the third-generation also known as self-inactivating (SIN) lentiviral vectors have been used in multiple clinical trials to introduce genes into targeted cells. The delivery of chimeric antigen receptors or cloned T-cell receptors using recombinant lentiviral vectors has achieved noteworthy clinical success in B-cell malignancies therapy. It leads to regulatory approval of the first genetically engineered cellular therapy based on the recombinant lentiviral vectors.
We also provide state-of-the-art lentivirus vector services from vector construction, characterization, to optimization and purification to meet the demands for basic research and gene therapy development.
Should you need further information, please feel free to contact us by E-mail for a quote and further discussion with our scientists.
