shRNA Lentivirus (self-inactivating), p7SK-(Arhgap22-shRNA-Seq1)(CAT#: LV-SI3926WQ)

This product is a Arhgap22-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Arhgap22 gene is Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. The expression of Arhgap22-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Arhgap22-shRNA-Seq1
Related Target/Protein Arhgap22
Region CDS
TargetSeq CCACTCAGATGTCAATAAGAT
NCBI RefSeq NM_153800
Alternative Names RhoGAP2; RhoGap22
Titer >1*10^10 GC/mL
Target Gene
Gene ID 58504
Uniprot ID Q7Z5H3

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