shRNA Lentivirus (self-inactivating), p7SK-(Mto1-shRNA-Seq1)(CAT#: LV-SI4024WQ)

This product is a Mto1-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The Mto1 gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The expression of Mto1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Mto1-shRNA-Seq1
Related Target/Protein Mto1
Region CDS
TargetSeq CAAAGTGCTAAACCGGCGTAA
NCBI RefSeq NM_026658
Alternative Names CGI-02; COXPD10
Titer >1*10^10 GC/mL
Related Diseases Deafness
Target Gene
Gene ID 25821
Uniprot ID Q9Y2Z2

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