shRNA Lentivirus (self-inactivating), pH1-(TMEM177-shRNA-Seq1)(CAT#: LV-SI2654WQ)

This product is a TMEM177-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The preotien encoded by TMEM177 gene plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation. The expression of TMEM177-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert TMEM177-shRNA-Seq1
Related Target/Protein TMEM177
Region CDS
TargetSeq CAGACACTTGTTCCGAATCAA
NCBI RefSeq NM_030577
Titer >1*10^10 GC/mL
Target Gene
Gene ID 80775
Uniprot ID Q53S58

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