shRNA Lentivirus (self-inactivating), pU6-(CXXC4-shRNA-Seq1)(CAT#: LV-SI0174WQ)
This product is a CXXC4-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The CXXC4 gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The expression of CXXC4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | CXXC4-shRNA-Seq1 |
Related Target/Protein | CXXC4 |
Region | CDS |
TargetSeq | CCGTCGTTGCAAATGGCAAAT |
NCBI RefSeq | NM_025212 |
Alternative Names | IDAX |
Titer | >1*10^10 GC/mL |
Related Diseases | Renal carcinoma |