shRNA Lentivirus (self-inactivating), pU6-(Gramd1a-shRNA-Seq1)(CAT#: LV-SI2214WQ)

This product is a Gramd1a-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Gramd1a gene is cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). The expression of Gramd1a-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Gramd1a-shRNA-Seq1
Related Target/Protein Gramd1a
Region CDS
TargetSeq CGAAGATTATTTCCACCACCT
NCBI RefSeq NM_027898
Titer >1*10^10 GC/mL
Related Diseases Cancer
Target Gene
Gene ID 57655
Uniprot ID Q96CP6

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