shRNA Lentivirus (self-inactivating), pU6-(KLHL7-shRNA-Seq1)(CAT#: LV-SI0062WQ)

This product is a KLHL7-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The KLHL7 encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42. The expression of KLHL7-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert KLHL7-shRNA-Seq1
Related Target/Protein KLHL7
Region 3UTR
TargetSeq CGCAGTATCTTAGCTCTAGAT
NCBI RefSeq NM_018846
Alternative Names CISS3; KLHL6; SBBI26
Titer >1*10^10 GC/mL
Related Diseases Retinitis pigmentosa
Target Gene
Gene ID 55975
Uniprot ID Q8IXQ5

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