shRNA Adeno-associated Virus Serotype 2, p7SK-(MICALCL-shRNA-Seq3)(CAT#: AAV-SI1088WQ)

This product is a MICALCL-shRNA encoding AAV, which is based on AAV-2 serotype. The MICALCL gene may cooperate with MAPK1/ERK2 via an intracellular signal transduction pathway in the morphogenetic development of round spermatids to spermatozoa and act as Rab effector protein and play a role in vesicle trafficking. The expression of MICALCL-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV-2
Backbone AAV-2
Tropism CNS, muscle, liver, brain, eye
Insert MICALCL-shRNA-Seq3
Related Target/Protein MICALCL
Region CDS
TargetSeq CCCAGCTTTCCTTGCAGTTAA
NCBI RefSeq NM_032867
Alternative Names Ebitein1
Titer >1*10^10 GC/mL
Related Diseases Renal cancer
Target Gene
Gene ID 84953
Uniprot ID Q6ZW33

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