shRNA Adeno-associated Virus Serotype 2, p7SK-(THOC1-shRNA-Seq1)(CAT#: AAV-SI1031WQ)

This product is a THOC1-shRNA encoding AAV, which is based on AAV-2 serotype. THOC1, also known as HPR1, is part of the TREX (transcription/export) complex and participate in an apoptotic pathway which is characterized by activation of caspase-6, increases in the expression of BAK1 and BCL2L1 and activation of NF-kappa-B. The expression of THOC1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.