shRNA Adeno-associated Virus Serotype 2, pH1-(Cenpc1-shRNA-Seq4)(CAT#: AAV-SI2592WQ)
This product is a Cenpc1-shRNA encoding AAV, which is based on AAV-2 serotype. The Cenpc1 gene is a centromere autoantigen and a component of the inner kinetochore plate. The encoded protein is required for maintaining proper kinetochore size and a timely transition to anaphase. The expression of Cenpc1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | Cenpc1-shRNA-Seq4 |
| Related Target/Protein | Cenpc1 |
| Region | CDS |
| TargetSeq | CCAAGAGTACAGAAGTCTTTA |
| NCBI RefSeq | NM_007683 |
| Alternative Names | MIF2; hcp-4; CENP-C; CENPC |
| Titer | >1*10^10 GC/mL |