shRNA Adeno-associated Virus Serotype 2, pH1-(OR5B17-shRNA-Seq7)(CAT#: AAV-SI3012WQ)
This product is a OR5B17-shRNA encoding AAV, which is based on AAV-2 serotype. The OR5B17 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR5B17-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | OR5B17-shRNA-Seq7 |
| Related Target/Protein | OR5B17 |
| Region | CDS |
| TargetSeq | GATTGTTTCAACACAAGAGTA |
| NCBI RefSeq | XM_166923 |
| Alternative Names | OR5B20P; OR11-237 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Olfactory dysfunction |