shRNA Adeno-associated Virus Serotype 2, pU6-(ARMC4-shRNA-Seq2)(CAT#: AAV-SI0088WQ)
This product is a ARMC4-shRNA encoding AAV, which is based on AAV-2 serotype. The ARMC4 gene encoded protein contains ten Armadillo repeat motifs (ARMs) and one HEAT repeat, and is thought to be involved in ciliary and flagellar movement. The expression of ARMC4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | ARMC4-shRNA-Seq2 |
| Related Target/Protein | ARMC4 |
| Region | CDS |
| TargetSeq | CACTGACAATAAAGAGCGGTT |
| NCBI RefSeq | NM_018076 |
| Alternative Names | CILD23 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Primary ciliary dyskensia (PCD) |
