shRNA Adeno-associated Virus Serotype 2, pU6-(CXXC4-shRNA-Seq1)(CAT#: AAV-SI0174WQ)

This product is a CXXC4-shRNA encoding AAV, which is based on AAV-2 serotype. The CXXC4 gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The expression of CXXC4-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV-2
Backbone AAV-2
Tropism CNS, muscle, liver, brain, eye
Insert CXXC4-shRNA-Seq1
Related Target/Protein CXXC4
Region CDS
TargetSeq CCGTCGTTGCAAATGGCAAAT
NCBI RefSeq NM_025212
Alternative Names IDAX
Titer >1*10^10 GC/mL
Related Diseases Renal carcinoma
Target Gene
Gene ID 80319
Uniprot ID Q9H2H0

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