shRNA Adeno-associated Virus Serotype 2, pU6-(Fdx1-shRNA-Seq1)(CAT#: AAV-SI2249WQ)
This product is a Fdx1-shRNA encoding AAV, which is based on AAV-2 serotype. The Fdx1 gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. The expression of Fdx1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | Fdx1-shRNA-Seq1 |
| Related Target/Protein | Fdx1 |
| Region | CDS |
| TargetSeq | GCCATTACTGATGAAGAGAAT |
| NCBI RefSeq | NM_007996 |
| Alternative Names | ADX; FDX; LOH11CR1D |
| Titer | >1*10^10 GC/mL |