shRNA Adeno-associated Virus Serotype 2, pU6-(Olfr446-shRNA-Seq1)(CAT#: AAV-SI2353WQ)

This product is a Olfr446-shRNA encoding AAV, which is based on AAV-2 serotype. The Olfr446 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of Olfr446-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV-2
Backbone AAV-2
Tropism CNS, muscle, liver, brain, eye
Insert Olfr446-shRNA-Seq1
Related Target/Protein Olfr446
Region CDS
TargetSeq GACTCAATCAAGTCGTTCTTT
NCBI RefSeq NM_146295
Alternative Names MOR261-12
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 258292
Uniprot ID Q8VEV0

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