shRNA Adeno-associated Virus Serotype 2, pU6-(OR5B12-shRNA-Seq2)(CAT#: AAV-SI1650WQ)

This product is a OR5B12-shRNA encoding AAV, which is based on AAV-2 serotype. The OR5B12 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of OR5B12-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV-2
Backbone AAV-2
Tropism CNS, muscle, liver, brain, eye
Insert OR5B12-shRNA-Seq2
Related Target/Protein OR5B12
Region CDS
TargetSeq CCACCATGACAACAAATGTAT
NCBI RefSeq XM_372409
Alternative Names OR5B16; OST743; OR5B12P; OR11-241
Titer >1*10^10 GC/mL
Related Diseases Olfactory dysfunction
Target Gene
Gene ID 390191
Uniprot ID Q96R08

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