shRNA Adeno-associated Virus Serotype 2, pU6-(TTC1-shRNA-Seq2)(CAT#: AAV-SI0145WQ)
This product is a TTC1-shRNA encoding AAV, which is based on AAV-2 serotype. The TTC1 gene encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. The expression of TTC1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV-2 |
| Backbone | AAV-2 |
| Tropism | CNS, muscle, liver, brain, eye |
| Insert | TTC1-shRNA-Seq2 |
| Related Target/Protein | TTC1 |
| Region | 3UTR |
| TargetSeq | CCTGATGTAATGAACCTAATT |
| NCBI RefSeq | NM_003314 |
| Alternative Names | TPR1 |
| Titer | >1*10^10 GC/mL |
| Related Diseases | Medullary Thyroid Cancer |
