Recombinant adeno-associated virus type 2, pU6-(Human IRAK2 3'UTR), Overexpression(CAT#: AAV-GTOH0041WQ)
The product is an adeno-associated virus type 2 (AAV2) vector containing the insertion of IRAK2 3'UTR gene. This IRAK2 gene encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV2 |
| Tropism | Both nondividing and dividing cells |
| Insert | IRAK2 3'UTR |
| Related Target/Protein | Human IRAK2 |
| NCBI RefSeq | NM_001570 |
| Alternative Names | IRAK-2 |
| Titer | >1.00E+12 v.g./mL |
| Application | Overexpression |
