Recombinant adeno-associated virus type 2, pU6-(Human papillomavirus HPV16-E5), Overexpression(CAT#: AAV-GTOH0020WQ)
The product is an adeno-associated virus type 2 (AAV2) vector containing the insertion of HPV16-E5 gene. This gene acts to keep host cells in a proliferation-competent state upon differentiation and enhances host epidermal growth factor receptor (EGFR) activation after stimulation by EGF by inhibiting EGFR internalization. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV2 |
Tropism | Both nondividing and dividing cells |
Insert | HPV16-E5 |
Related Target/Protein | Human papillomavirus type 16, E5 |
NCBI RefSeq | GI:482671891 |
Titer | >1.00E+12 v.g./mL |
Application | Overexpression |