Recombinant adeno-associated virus type 2, pU6-(Human papillomavirus HPV16-E5), Overexpression(CAT#: AAV-GTOH0020WQ)

Datasheet

The product is an adeno-associated virus type 2 (AAV2) vector containing the insertion of HPV16-E5 gene. This gene acts to keep host cells in a proliferation-competent state upon differentiation and enhances host epidermal growth factor receptor (EGFR) activation after stimulation by EGF by inhibiting EGFR internalization. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.

Specifications
Family Parvoviridae
Species Adeno-associated virus (AAV)
Serotype AAV2
Tropism Both nondividing and dividing cells
Insert HPV16-E5
Related Target/Protein Human papillomavirus type 16, E5
NCBI RefSeq GI:482671891
Titer >1.00E+12 v.g./mL
Application Overexpression
Target Gene
Gene ID 1489077
Uniprot ID P06927

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