Recombinant adeno-associated virus type 2, pU6-(Human PAX8 3'UTR WT), Overexpression(CAT#: AAV-GTOH0018WQ)
The product is an adeno-associated virus type 2 (AAV2) vector containing the insertion of PAX8 3'UTR WT gene. This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.
| Specifications | |
|---|---|
| Family | Parvoviridae |
| Species | Adeno-associated virus (AAV) |
| Serotype | AAV2 |
| Tropism | Both nondividing and dividing cells |
| Insert | PAX8 3'UTR WT |
| Related Target/Protein | Human PAX8 |
| NCBI RefSeq | NM_003466 |
| Titer | >1.00E+12 v.g./mL |
| Related Diseases | thyroid dysgenesis, thyroid follicular carcinomas, atypical follicular thyroid adenomas |
| Application | Overexpression |