Recombinant adeno-associated virus type 2, pU6-(Human slug), Overexpression(CAT#: AAV-GTOH0030WQ)
The product is an adeno-associated virus type 2 (AAV2) vector containing the insertion of slug gene. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. The product is suitable for stable overexpression of exogenous gene in various types of cells and can be used in gene therapy research and development.
Specifications | |
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Family | Parvoviridae |
Species | Adeno-associated virus (AAV) |
Serotype | AAV2 |
Tropism | Both nondividing and dividing cells |
Insert | slug |
Related Target/Protein | Human SNAI2 |
NCBI RefSeq | NM_003068 |
Alternative Names | SLUG, WS2D, SLUGH, SLUGH1, SNAIL2 |
Titer | >1.00E+12 v.g./mL |
Related Diseases | breast carcinoma, sporatic cases of neural tube defects |
Application | Overexpression |