siRNA, Anti-DHRS7, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT76227WQ-2OMe)

The product SIRGT76227WQ-2OMe is a type of small interfering RNA (siRNA) that targets DHRS7 gene and regulates the expression of gene. The siRNA interferes with the expression of DHRS7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016029.3
Alternative Names CGI-86; SDR34C1; retDSR4; retSDR4
Related Diseases Hyperalphalipoproteinemia 1
Purification HPLC
Target Gene
Gene ID 51635
Uniprot ID Q9Y394
Sub Cat Target Species Modification Scale  
SIRGT77227WQ-2F DHRS7 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT78227WQ-2MOE DHRS7 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT79227WQ-LNA DHRS7 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76227WQ-RB DHRS7 Human Ribo-modified Inquiry
SIRGT77227WQ-BB DHRS7 Human Backbone-modified Inquiry

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