siRNA, Anti-MECR, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT76465WQ-2OMe)

The product SIRGT76465WQ-2OMe is a type of small interfering RNA (siRNA) that targets MECR gene and regulates the expression of gene. The siRNA interferes with the expression of MECR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_016011.4
Alternative Names CGI-63; DYTOABG; ETR1; FASN2B; NRBF1
Related Diseases 3-Methylglutaconic Aciduria, Type Iii
Purification HPLC
Target Gene
Gene ID 51102
Uniprot ID Q9BV79
Sub Cat Target Species Modification Scale  
SIRGT79465WQ-LNA MECR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT76465WQ-RB MECR Human Ribo-modified Inquiry
SIRGT77465WQ-BB MECR Human Backbone-modified Inquiry

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